Serveur d'exploration sur le lymphœdème

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

Lymphedema: An immunologically vulnerable site for development of neoplasms

Identifieur interne : 009888 ( Main/Exploration ); précédent : 009887; suivant : 009889

Lymphedema: An immunologically vulnerable site for development of neoplasms

Auteurs : Vincenzo Ruocco [Italie] ; Robert A. Schwartz [États-Unis] ; Eleonora Ruocco [Italie]

Source :

RBID : Pascal:02-0512046

Descripteurs français

English descriptors

Abstract

Lymphedema is the result of accumulation of protein-rich interstitial fluid (lymph stasis) caused by a failure of lymph drainage in the face of a normal capillary filtration. Whether the origin is congenital or acquired from infection, radiation, trauma, or surgery, chronic lymph stasis impairs local immune surveillance by disrupting trafficking of the immunocompetent cells in the lymphedematous district and stimulates vicarious angiogenesis by promoting development of a collateral lymphatic and hematic network in the lymphedematous district. When the local mechanisms of immune surveillance begin to fail, the lymphedematous region becomes an immunologically vulnerable area, predisposed to malignancy, chiefly vascular tumors such as Stewart-Treves syndrome and Kaposi's sarcoma, because of the continual angiogenic stimulus.


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en" level="a">Lymphedema: An immunologically vulnerable site for development of neoplasms</title>
<author>
<name sortKey="Ruocco, Vincenzo" sort="Ruocco, Vincenzo" uniqKey="Ruocco V" first="Vincenzo" last="Ruocco">Vincenzo Ruocco</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>Department of Dermatology, 2nd University of Naples</s1>
<s3>ITA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<wicri:noRegion>Department of Dermatology, 2nd University of Naples</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Schwartz, Robert A" sort="Schwartz, Robert A" uniqKey="Schwartz R" first="Robert A." last="Schwartz">Robert A. Schwartz</name>
<affiliation wicri:level="1">
<inist:fA14 i1="02">
<s1>Department of Dermatology, New Jersey Medical School</s1>
<s2>Newark</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Newark</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Ruocco, Eleonora" sort="Ruocco, Eleonora" uniqKey="Ruocco E" first="Eleonora" last="Ruocco">Eleonora Ruocco</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>Department of Dermatology, 2nd University of Naples</s1>
<s3>ITA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<wicri:noRegion>Department of Dermatology, 2nd University of Naples</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">INIST</idno>
<idno type="inist">02-0512046</idno>
<date when="2002">2002</date>
<idno type="stanalyst">PASCAL 02-0512046 INIST</idno>
<idno type="RBID">Pascal:02-0512046</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000740</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000220</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000762</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000762</idno>
<idno type="wicri:doubleKey">0190-9622:2002:Ruocco V:lymphedema:an:immunologically</idno>
<idno type="wicri:Area/Main/Merge">009C74</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:12077591</idno>
<idno type="wicri:Area/PubMed/Corpus">004548</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">004548</idno>
<idno type="wicri:Area/PubMed/Curation">004548</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">004548</idno>
<idno type="wicri:Area/PubMed/Checkpoint">004548</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">004548</idno>
<idno type="wicri:Area/Ncbi/Merge">000A08</idno>
<idno type="wicri:Area/Ncbi/Curation">000A08</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000A08</idno>
<idno type="wicri:doubleKey">0190-9622:2002:Ruocco V:lymphedema:an:immunologically</idno>
<idno type="wicri:Area/Main/Merge">009770</idno>
<idno type="wicri:Area/Main/Curation">009888</idno>
<idno type="wicri:Area/Main/Exploration">009888</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title xml:lang="en" level="a">Lymphedema: An immunologically vulnerable site for development of neoplasms</title>
<author>
<name sortKey="Ruocco, Vincenzo" sort="Ruocco, Vincenzo" uniqKey="Ruocco V" first="Vincenzo" last="Ruocco">Vincenzo Ruocco</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>Department of Dermatology, 2nd University of Naples</s1>
<s3>ITA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<wicri:noRegion>Department of Dermatology, 2nd University of Naples</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Schwartz, Robert A" sort="Schwartz, Robert A" uniqKey="Schwartz R" first="Robert A." last="Schwartz">Robert A. Schwartz</name>
<affiliation wicri:level="1">
<inist:fA14 i1="02">
<s1>Department of Dermatology, New Jersey Medical School</s1>
<s2>Newark</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Newark</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Ruocco, Eleonora" sort="Ruocco, Eleonora" uniqKey="Ruocco E" first="Eleonora" last="Ruocco">Eleonora Ruocco</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>Department of Dermatology, 2nd University of Naples</s1>
<s3>ITA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<wicri:noRegion>Department of Dermatology, 2nd University of Naples</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series>
<title level="j" type="main">Journal of the American Academy of Dermatology</title>
<title level="j" type="abbreviated">J. Am. Acad. Dermatol.</title>
<idno type="ISSN">0190-9622</idno>
<imprint>
<date when="2002">2002</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt>
<title level="j" type="main">Journal of the American Academy of Dermatology</title>
<title level="j" type="abbreviated">J. Am. Acad. Dermatol.</title>
<idno type="ISSN">0190-9622</idno>
</seriesStmt>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Angiosarcoma</term>
<term>Carcinogenesis</term>
<term>Dysfunction</term>
<term>Female</term>
<term>Hemangiosarcoma (immunology)</term>
<term>Hemangiosarcoma (pathology)</term>
<term>Human</term>
<term>Humans</term>
<term>Immune response</term>
<term>Immunocompromised Host</term>
<term>Kaposi sarcoma</term>
<term>Lymphedema</term>
<term>Lymphedema (immunology)</term>
<term>Lymphedema (pathology)</term>
<term>Male</term>
<term>Precancerous Conditions (immunology)</term>
<term>Precancerous Conditions (pathology)</term>
<term>Prognosis</term>
<term>Review</term>
<term>Risk Assessment</term>
<term>Sarcoma</term>
<term>Sarcoma, Kaposi (immunology)</term>
<term>Sarcoma, Kaposi (pathology)</term>
<term>Skin Neoplasms (immunology)</term>
<term>Skin Neoplasms (pathology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Femelle</term>
<term>Humains</term>
<term>Hémangiosarcome (anatomopathologie)</term>
<term>Hémangiosarcome (immunologie)</term>
<term>Lymphoedème (anatomopathologie)</term>
<term>Lymphoedème (immunologie)</term>
<term>Mâle</term>
<term>Pronostic</term>
<term>Sarcome de Kaposi (anatomopathologie)</term>
<term>Sarcome de Kaposi (immunologie)</term>
<term>Sujet immunodéprimé</term>
<term>Tumeurs cutanées (anatomopathologie)</term>
<term>Tumeurs cutanées (immunologie)</term>
<term>États précancéreux (anatomopathologie)</term>
<term>États précancéreux (immunologie)</term>
<term>Évaluation des risques</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr">
<term>Hémangiosarcome</term>
<term>Lymphoedème</term>
<term>Sarcome de Kaposi</term>
<term>Tumeurs cutanées</term>
<term>États précancéreux</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr">
<term>Hémangiosarcome</term>
<term>Lymphoedème</term>
<term>Sarcome de Kaposi</term>
<term>Tumeurs cutanées</term>
<term>États précancéreux</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en">
<term>Hemangiosarcoma</term>
<term>Lymphedema</term>
<term>Precancerous Conditions</term>
<term>Sarcoma, Kaposi</term>
<term>Skin Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Hemangiosarcoma</term>
<term>Lymphedema</term>
<term>Precancerous Conditions</term>
<term>Sarcoma, Kaposi</term>
<term>Skin Neoplasms</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Female</term>
<term>Humans</term>
<term>Immunocompromised Host</term>
<term>Male</term>
<term>Prognosis</term>
<term>Risk Assessment</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr">
<term>Femelle</term>
<term>Humains</term>
<term>Lymphoedème</term>
<term>Angiosarcome</term>
<term>Mâle</term>
<term>Pronostic</term>
<term>Sarcome Kaposi</term>
<term>Sujet immunodéprimé</term>
<term>Trouble fonctionnel</term>
<term>Réponse immune</term>
<term>Article synthèse</term>
<term>Carcinogenèse</term>
<term>Homme</term>
<term>Sarcome</term>
<term>Évaluation des risques</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr">
<term>Homme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Lymphedema is the result of accumulation of protein-rich interstitial fluid (lymph stasis) caused by a failure of lymph drainage in the face of a normal capillary filtration. Whether the origin is congenital or acquired from infection, radiation, trauma, or surgery, chronic lymph stasis impairs local immune surveillance by disrupting trafficking of the immunocompetent cells in the lymphedematous district and stimulates vicarious angiogenesis by promoting development of a collateral lymphatic and hematic network in the lymphedematous district. When the local mechanisms of immune surveillance begin to fail, the lymphedematous region becomes an immunologically vulnerable area, predisposed to malignancy, chiefly vascular tumors such as Stewart-Treves syndrome and Kaposi's sarcoma, because of the continual angiogenic stimulus.</div>
</front>
</TEI>
<affiliations>
<list>
<country>
<li>Italie</li>
<li>États-Unis</li>
</country>
</list>
<tree>
<country name="Italie">
<noRegion>
<name sortKey="Ruocco, Vincenzo" sort="Ruocco, Vincenzo" uniqKey="Ruocco V" first="Vincenzo" last="Ruocco">Vincenzo Ruocco</name>
</noRegion>
<name sortKey="Ruocco, Eleonora" sort="Ruocco, Eleonora" uniqKey="Ruocco E" first="Eleonora" last="Ruocco">Eleonora Ruocco</name>
</country>
<country name="États-Unis">
<noRegion>
<name sortKey="Schwartz, Robert A" sort="Schwartz, Robert A" uniqKey="Schwartz R" first="Robert A." last="Schwartz">Robert A. Schwartz</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 009888 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 009888 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Pascal:02-0512046
   |texte=   Lymphedema: An immunologically vulnerable site for development of neoplasms
}}

Wicri

This area was generated with Dilib version V0.6.31.
Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024